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Originally identified in December 2019 in Wuhan, China, SARS-CoV-2 has become a pandemic owing to a long period of incubation, a high number of asymptomatic cases, and high international mobility. Here we consider the unique conjunction of events that allowed this new coronavirus to emerge and create a pandemic. We urge governments to learn from SARS and COVID-19 and to implement preparedness for pandemics to come.