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Microscopy Techniques for SARS-CoV-2 Visualization
Electron microscopy is the indispensable tool employed by scientists to examine the intricate structure of SARS-CoV-2, the causative agent of COVID-19.
Specifically, transmission electron microscopy (TEM) offers detailed insights into the virus's internal components, including its protein coat (capsid) and genetic material (RNA). Conversely, scanning electron microscopy (SEM) provides high-resolution, three-dimensional images of the virus's external morphology, facilitating studies on its interaction with host cells.
Given the diminutive size of viruses, conventional light microscopy is inadequate for such investigations.
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