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A reaction occurs when two substances are combined due to the interactions between their chemical properties. These interactions lead to the breaking and forming of chemical bonds, resulting in the creation of new substances with different properties from the original reactants. This process can be driven by factors such as changes in temperature, pressure, or the presence of a catalyst. For example, when vinegar (acetic acid) and baking soda (sodium bicarbonate) are mixed, they react to form carbon dioxide gas, water, and sodium acetate, demonstrating a typical chemical reaction where new substances are produced from the original reactants.